Recombinant Rat M-CSF

Description

EnkiLife provides the Recombinant Rat M-CSF protein,aslo know as Macrophage colony-stimulating factor 1,CSF-1,M-CSF,MCSF,CSF1, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Rat Macrophage Colony-stimulating Factor 1 is produced by our Mammalian expression system and the target gene encoding Glu33-Arg254 is expressed.Accession:Q8JZQ0. Expression Host:Human Cells.Species:Rat.Predicted Molecular Mass:25.2 KDa. Background:Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipoprotein clearance.