Recombinant Rhesus Macaque CD27 (C-6His)

Description

EnkiLife provides the Recombinant Rhesus Macaque CD27 (C-6His) protein,aslo know as CD27 Antigen,CD27L Receptor,T-Cell Activation Antigen CD27,T14,Tumor Necrosis Factor Receptor Superfamily Member 7,CD27,CD27,TNFRSF7, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Rhesus Macaque CD27 Molecule is produced by our Mammalian expression system and the target gene encoding Thr21-Ile192 is expressed with a 6His tag at the C-terminus.Accession:F7BYS2. Expression Host:Human Cells.Species:Rhesus macaque.Predicted Molecular Mass:20.1 KDa. Background:CD27 antigen, also known as CD27L receptor, T-cell activation antigen CD27, T14, S152, Tp55, TNFRSF7 and Tumor necrosis factor receptor for superfamily member 7，belongs to the TNF-receptor superfamily. CD27 is a single-pass type I membrane protein and exists as a homodimer form, containing three TNFR-Cys repeats. CD27 transduces signals that lead to the activation of NF-KappaB and MAPK8/JNK. CD27 is involved in regulating B-cell activation and immunoglobulin synthesis, binding to the ligand CD70. TRAF2 and TRAF5 have been shown to mediate the signaling process of CD27. CD27-binding protein (SIVA), which is a proapoptotic protein, can bind to CD27 and is thought to play a key role in the apoptosis. CD27 is required for generation and long-term maintenance of T cell immunity.