Recombinant Rhesus Macaque IL-33 (N-6His)

Description

EnkiLife provides the Recombinant Rhesus Macaque IL-33 (N-6His) protein,aslo know as Interleukin-33,IL-33,Interleukin-1 Family Member 11,IL-1F11,Nuclear Factor From High Endothelial Venules,NF-HEV,IL33,C9orf26,IL1F11,NFHEV, which features high purity, high activity, and high stability. It can be applied in scientific research, biopharmaceuticals, and other fields.Purity:Greater than 95% as determined by reducing SDS-PAGE;Endotoxin Level:<1 EU/µg as determined by LAL test.;Construction:Recombinant Rhesus Macaque Interleukin 33 is produced by our E.coli expression system and the target gene encoding Ser112-Ile270 is expressed with a 6His tag at the N-terminus.Accession:F7DLG4. Expression Host:E.coli.Species:Rhesus macaque.Predicted Molecular Mass:20.3 KDa. Background:Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.