rel-Cleroindicin F

Description

rel-Cleroindicin F Rengyolone is a cyclohexyl acetyl compound that can be isolated from the fruit of forsythia and has anti-inflammatory activity. It strongly inhibits the production of nitric oxide NO and tumor necrosis factor-alpha TNF-? . rel-Cleroindicin F does this by downregulating the activity of NF-?B and NF-?B kinases in RAW 264.7 cells stimulated by LPS HY-D1056 , thus inhibiting the expression of inducible nitric oxide synthase NO Synthase and nitric oxide production.