GENERAL CATALOGUE
rel-SB-612111 hydrochloride
HY-18617 · 50 mg
MedChemExpress · Cat: HY-18617
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Manufacturer product page
medchemexpress.com/rel-sb-612111-hydrochloride.htmlCatalog No: HY-18617
CAS No: 371980-94-8
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
rel-SB-612111 hydrochloride is a novel and potent human opiate receptor-like orphan receptor ORL-1 antagonist with a high affinity for hORL-1 Ki=0.33 nM . rel-SB-612111 hydrochloride exhibits selectivity for ?-, ?- and ?-receptors with Ki values of 57.6 nM, 160.5 nM and 2109 nM, respecticely. rel-SB-612111 hydrochloride effectively antagonizes the pronociceptive action of Nociceptin HY-P0183 in an acute pain model.
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