GENERAL CATALOGUE
Rencofilstat
HY-135644 · 1 mg
MedChemExpress · Cat: HY-135644
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Catalog No: HY-135644
CAS No: 1383420-08-3
Category: Cell Cycle DNA Damage
Pack Size: 1 mg
Brand: MedChemExpress
Description
Rencofilstat CRV431 is an orally active pan-cyclophilin inhibitor with IC50 values of 2.5 nM, 3.1 nM, 2.8 nM, 7.3 nM for Cyp A, CypB, Cyp D and Cyp G, respectively. Rencofilstat reduces fibrosis and tumor growth in models of chronic liver disease. Rencofilstat can be used for the study of nonalcoholic steatohepatitis NASH , hepatocellular carcinoma and viral hepatitis-induced liver disease.
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