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RepSox, TGF-beta type 1 receptor inhibitor
ab142139 · 5 mg
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Catalog No: ab142139
Category: Biochemicals
Pack Size: 5 mg
Brand: abcam
Description
MW 287.32 Da, Purity >98 %. Selective TGF-beta type 1 receptor and ALK5 autophosphorylation inhibitor IC50 = 4 nM for ALK5 . Selective for ALK5 over a range of other kinases, including p38 MAPK, JNK1 and GSK3. Replaces Sox2 for reprogramming iPSCs. Active in vitro and in vivo. Cell-permeable . .
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