GENERAL CATALOGUE
Resatorvid
HY-11109 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-11109
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medchemexpress.com/TAK-242.html
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Catalog No: HY-11109
CAS No: 243984-11-4
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Resatorvid TAK-242 is a selective Toll-like receptor 4 TLR4 inhibitor. Resatorvid inhibits NO, TNF-AZA+/- and IL-6 production with IC50s of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy and plays pivotal role in various inflammatory diseases.
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