GENERAL CATALOGUE
Retosiban
HY-14778 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-14778
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Catalog No: HY-14778
CAS No: 820957-38-8
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Retosiban GSK221149A is a potent, selective, and orally active oxytocin receptor antagonist Ki hOT = 0.65 nM, Ki rOT = 4.1 nM with no detectable agonist activity. Retosiban has nanomolar affinity for the oxytocin receptor with >1400-fold selectivity over the closely related vasopressin receptors. Retosiban inhibits spontaneous and induces uterine contractions. Retosiban can be studied in research for preterm labour.
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