GENERAL CATALOGUE
RETRA hydrobromide
HY-113843 · 50 mg
MedChemExpress · Cat: HY-113843
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Manufacturer product page
medchemexpress.com/retra-hydrobromide.htmlCatalog No: HY-113843
CAS No: 1035875-01-4
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
RETRA hydrobromide is a mutant p53-dependent activator of p73 that can inhibit cancer cells carrying mutant p53. RETRA hydrobromide increases the expression level of p73, induces transcriptional activation of several common to transcriptional targets p53 and p73, which leads to mutant p53- and p73-dependent inhibition of tumor growth, reduction of colony formation and induction of effector caspases.
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