GENERAL CATALOGUE
Rhapontin
HY-N0671 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-N0671
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Catalog No: HY-N0671
CAS No: 155-58-8
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Rhapontin Rhaponiticin is an orally aactive SIRT1 agonist and AMPK activator with anti-inflammatory and anti-fibrotic activities. Rhapontin inhibits NLRP3 inflammasome activation by activating SIRT1 and inhibits TGF-?/Smad signaling via the AMPK pathway. Rhapontin reduces intestinal and lung inflammation, inhibits fibroblast differentiation and extracellular matrix deposition, and enhances tight junction protein expression to repair epithelial barriers. Rhapontin can be used in the study of inflammatory bowel diseases such as ulcerative colitis and pulmonary fibrosis.
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