GENERAL CATALOGUE
Rhosin hydrochloride
HY-12646 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-12646
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Manufacturer product page
medchemexpress.com/Rhosin-hydrochloride.htmlCatalog No: HY-12646
CAS No: 1281870-42-5
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Rhosin hydrochloride is a potent, specific RhoA subfamily Rho GTPases inhibitor. Rhosin hydrochloride specifically binds to RhoA to inhibit RhoA-GEF interaction with a Kd of 0.4 uM, and does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin hydrochloride induces cell apoptosis. Rhosin hydrochloride promotes stress resiliency through enhancing D1-MSN plasticity and reducing hyperexcitability.
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