GENERAL CATALOGUE
Rigosertib
HY-12037A · 5 mg
MedChemExpress · Cat: HY-12037A
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medchemexpress.com/rigosertib.htmlCatalog No: HY-12037A
CAS No: 592542-59-1
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
Rigosertib ON-01910 is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3 kinase/Akt pathway, promots the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle. Rigosertib is a selective and non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM.