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Rigosertib sodium
GENERAL CATALOGUE

Rigosertib sodium

HY-12037 · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-12037

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Catalog No: HY-12037
CAS No: 592542-60-4
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress

Description

Rigosertib sodium ON-01910 sodium is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3K/Akt pathway, promotes the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle. Rigosertib sodium is a selective and non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM.

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