GENERAL CATALOGUE
Rineterkib
HY-114491 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-114491
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medchemexpress.com/ERK-IN-1.html
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Catalog No: HY-114491
CAS No: 1715025-32-3
Category: MAPK ERK Pathway
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Rineterkib compound B is an orally available ERK1 and ERK2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer CRC and KRAS-mutant ovarian cancer. Rineterkib hydrochloride can also inhibit RAF.
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