GENERAL CATALOGUE
Rineterkib hydrochloride
HY-114491A · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-114491A
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medchemexpress.com/rineterkib-hydrochloride.html
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Catalog No: HY-114491A
CAS No: 1715025-34-5
Category: MAPK ERK Pathway
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Rineterkib hydrochloride compound B is an orally available ERK1 and ERK2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer CRC and KRAS-mutant ovarian cancer. Rineterkib hydrochloride can also inhibit RAF.
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