GENERAL CATALOGUE
Ripretinib
HY-112306 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-112306
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Manufacturer product page
medchemexpress.com/DCC-2618.htmlCatalog No: HY-112306
CAS No: 1442472-39-0
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Ripretinib DCC-2618 is an orally bioavailable, selective KIT and PDGFRA switch-control inhibitor. Ripretinib DCC-2618 targets and binds to both wild-type and mutant forms of KIT and PDGFRA specifically at their switch pocket binding sites, thereby preventing the switch from inactive to active conformations of these kinases and inactivating their wild-type and mutant forms. Ripretinib DCC-2618 also inhibits multiple other kinase targets, such as FLT3 and KDR or VEGFR-2 . DCC-2618 exerts antineoplastic effect and induces apoptosis.
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