RLP-CRE-ZsGreen1-11

Description

Cre-ZsGreen1 RLPs RNAlentiviralparticles consist of biologically active Cre recombinase and ZsGreen1 mRNAs packaged into nonintegrating, virus-like particles, and are used to mediate a transient burst of Cre and fluorescent protein expression for a wide array ofin vitroandin vivoapplications involving Cre-Lox recombination. Footprint-free Cre delivery via RLPs avoids the risks of random genomic integration and persistent Cre expression associated with viral transduction, and the cellular toxicity and target-cell limitations attributed to RNA or plasmid-based transfection. Cre-ZsGreen1 RLPs are generated using a novel packaging technology that employs a phage RNA-binding protein to load multiple mature mRNA molecules per particle. RLPs have been demonstrated to yield robust Cre and ZsGreen1 expression with high efficiency in cell lines, primary cells, stem cells, tissues, and organisms. Our products are to be used forResearch Use Only. They may not be used for any other purpose, including, but not limited to, use in humans, therapeutic or diagnostic use, or commercial use of any kind. Our products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products or to provide a service to third parties without our prior written approval. Back Back Back