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RMC-4998 formic
GENERAL CATALOGUE

RMC-4998 formic

HY-156671A · 1 mg

MedChemExpress · Cat: HY-156671A

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Catalog No: HY-156671A
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress

Description

RMC-4998 formic is an orally active inhibitor targeting the active or GTP-bound state of the KRASG12C mutant. RMC-4998 formic can form a ternary complex with intracellular CYPA and the activated KRASG12C mutant, with an IC50 value of 28 nM. RMC-4998 formic can inhibit ERK signaling in KRASG12C mutant cancer cells and induce apoptosis. RMC-4998 formic can be used for non-small cell lung cancer NSCLC research.

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