

HY-146097 · 50 mg
MedChemExpress · Cat: HY-146097
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medchemexpress.com/rms5.html
Description
RMS5, a tetrandrine analogue, is a potent P-glycoprotein P-gp inhibitor. RMS5 has markedly antiproliferative and cytotoxic effects on cancer cells. RMS5 slightly diminishes the expression of the anti-apoptotic Bcl-2 family proteins Bcl-XL and Mcl-1. RMS3 causes PARP cleavage, a marker for cells undergoing apoptosis. RMS5 has strong anticancer property.







