RNase R

Description

Save when you buy abms RNase R bundled with RNaseOFF Ribonuclease Inhibitor. Click here and add this bundle to your cart to save instantly RNase R is an E. coli exoribonuclease that exhibits 3-to-5 exonuclease activity, efficiently digesting nearly all linear RNA species. This enzyme does not digest circular, lariat, or double-stranded RNA with short 3 overhangs less than seven nucleotides . As such, this enzyme is ideally suited to the study of lariat RNA produced by traditional splicing, as well as circRNAs which arise through back-splicing. By removing linear RNAs from cellular or RNA extracts, RNase R greatly facilitates the identification of circular species through RNA-sequencing. This enables researchers to probe the landscape of splicing events with greater depth. Product Component Quantity RNase R 10 U/mul 50 mul 10X RNase R Reaction Buffer 1.0 ml