RNase R with RNaseOFF Bundle

Description

Pair one of abms best-selling products with our high performance RNaseOFF Ribonuclease Inhibitor RNase R Cat. No. E049 is an E. coli exoribonuclease that exhibits 3-to-5 exonuclease activity, efficiently digesting nearly all linear RNA species. This enzyme does not digest circular, lariat, or double-stranded RNA with short 3 overhangs less than seven nucleotides . As such, this enzyme is ideally suited to the study of lariat RNA produced by traditional splicing, as well as circRNAs which arise through back-splicing. By removing linear RNAs from cellular or RNA extracts, RNase R greatly facilitates the identification of circular species through RNA-sequencing. This enables researchers to probe the landscape of splicing events with greater depth. To further the protection and enhancement of circRNAs, this bundle includes our high performance RNaseOFF Ribonuclease Inhibitor Cat. No. G138S for one special price This bundle includes: RNase R 500 U,10 U/mul 10X RNase R Reaction Buffer RNaseOFF Ribonuclease Inhibitor 800 U, 40 U/mul