RNF8 Rabbit Monoclonal Antibody

Description

EnkiLife offers the RNF8 Rabbit Monoclonal Antibody. This antibody reacts with Human,Rat species and is suitable for WB application. Alternative Names of Immunogen: C3HC4 type zinc finger protein; RNF8;;RNF8. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1000-1:2000 Background: E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites.