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Ro 67-4853
GENERAL CATALOGUE

Ro 67-4853

HY-107506 · 1 mg

MedChemExpress · Cat: HY-107506

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medchemexpress.com/ro-67-4853.html
Catalog No: HY-107506
CAS No: 302841-89-0
Category: GPCR G Protein
Pack Size: 1 mg
Brand: MedChemExpress

Description

Ro 67-4853 is a positive allosteric modulator PAM of mGluR1 pEC50=7.16 for rmGlu1a receptor . Ro67-4853 exhibits activity at all group I mGlu receptors including hmGlu1, rmGlu1, and rmGlu5. Ro 67-4853 enhances the potency of L-Glu by interacting with the transmembrane domain TMD of the receptor. Ro 67-4853 potentiates sensory synaptic responses to repetitive vibrissa stimulation.

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