GENERAL CATALOGUE
Ro 67-7476
HY-100403 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-100403
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Manufacturer product page
medchemexpress.com/Ro-67-7476.htmlCatalog No: HY-100403
CAS No: 298690-60-5
Category: GPCR G Protein
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Ro 67-7476 is a potent positive allosteric modulator of mGluR1 and potentiates glutamate-induced calcium release in HEK293 cells expressing rat mGluR1a with an EC50 of 60.1 nM. Ro 67-7476 is a potent P-ERK1/2 agonist and activates ERK1/2 phosphorylation in the absence of exogenously added glutamate EC50=163.3 nM .
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