GENERAL CATALOGUE
RO2959 hydrochloride
HY-113618A · 1 mg
MedChemExpress · Cat: HY-113618A
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Catalog No: HY-113618A
CAS No: 1219927-22-6
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
RO2959 hydrochloride is a potent and selective CRAC channel inhibitor with an IC50 of 402 nM. RO2959 hydrochloride is a potent blocker of store operated calcium entry SOCE mediated by Orai1/Stim1 channels with an IC50 of 25 nM. RO2959 hydrochloride is also a potent inhibitor of human IL-2 production, and potently blocks T cell receptor triggered gene expression and T cell functional pathways.
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