GENERAL CATALOGUE
RO2959 monohydrochloride
HY-113618B · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-113618B
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medchemexpress.com/ro2959-monohydrochloride.htmlCatalog No: HY-113618B
CAS No: 2309172-44-7
Category: Immunology Inflammation
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
RO2959 monohydrochloride is a potent and selective CRAC channel inhibitor with an IC50 of 402 nM. RO2959 monohydrochloride is a potent blocker of store operated calcium entry SOCE mediated by Orai1/Stim1 channels with an IC50 of 25 nM. RO2959 monohydrochloride is also a potent inhibitor of human IL-2 production, and potently blocks T cell receptor triggered gene expression and T cell functional pathways.
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