

HY-129274 · 50 mg
MedChemExpress · Cat: HY-129274
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medchemexpress.com/ro4988546.html
Description
RO4988546 is a negative allosteric modulator NAM that targets metabotropic glutamate receptors 2 and 3 mGlu2, mGlu3 . RO4988546 can reduce the binding of 3h -LY354740 at the positive binding site, while affecting the receptors G protein coupling and intracellular signaling. RO4988546 can be used in the development of antidepressants and cognitive enhancers.







