GENERAL CATALOGUE
RO5353
HY-12580 · 50 mg
MedChemExpress · Cat: HY-12580
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medchemexpress.com/ro5353.html
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Catalog No: HY-12580
CAS No: 1360821-61-9
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
RO5353 is an orally active inhibitor for p53-MDM2 with an IC50 of 7 nM for MDM2. RO5353 inhibits the proliferation of wild-type p53 cancer cells with an average IC50 of 7 nM. RO5353 exhibits antitumor efficacy and good pharmacokinetic characteristics in mice.
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