RO60 Rabbit Polyclonal Antibody

Description

EnkiLife offers the RO60 Rabbit Polyclonal Antibody. This antibody reacts with Human,Rat,Mouse species and is suitable for WB,IHC application. Alternative Names of Immunogen: TROVE2; RO60; SSA2; 60 kDa SS-A/Ro ribonucleoprotein; 60 kDa Ro protein; 60 kDa ribonucleoprotein Ro; RoRNP; Ro 60 kDa autoantigen; Sjoegren syndrome antigen A2; Sjoegren syndrome type A antigen; SS-A; TROVE domain family member 2. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:50-1:300 Background: disease:Sera from patients with systemic lupus erythematosus (SLE) often contain antibodies that react with the normal cellular SSA2 protein as if this antigen was foreign. function:RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation. PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. similarity:Belongs to the Ro 60 kDa family. similarity:Contains 1 TROVE domain. subunit:Found in a complex with PUF60 and Y5 RNA. Interacts with RIP11. Research Area:Systemic lupus erythematosus;