GENERAL CATALOGUE
Rofecoxib
HY-17372 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-17372
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Catalog No: HY-17372
CAS No: 162011-90-7
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Rofecoxib is a potent, specific and orally active COX-2 inhibitor, with IC50s of 26 and 18 nM for human COX-2 in human osteosarcoma cells and Chinese hamster ovary cells, with a 1000-fold selectivity for COX-2 over human COX-1 IC50 50 ?M in U937 cells and > 15 ?M in Chinese hamster ovary cells.
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