Romidepsin

Description

Romidepsin GMP FK 228 GMP is Romidepsin HY-15149 produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Romidepsin FK 228 is a Histone deacetylase HDAC inhibitor with anti-tumor activities. Romidepsin FK 228 inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC50s of 36 nM, 47 nM, 510 nM and 1.4 ?M, respectively. Romidepsin FK 228 is produced by Chromobacterium violaceum, induces cell G2/M phase arrest and apoptosis.