GENERAL CATALOGUE
ROS1 Stable Ba/F3 Cell Line
T3085 · 1 x 106 cells / 1.0 mL
abm good · Cat: T3085
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Catalog No: T3085
Category: Cellular Materials
Pack Size: 1 x 106 cells / 1.0 mL
Brand: abm good
Description
Fusing a kinase domain to a homodimerization domain such as the PNT domain of ETV6 can result in activated kinase. The ROS1 Stable Ba/F3 Cell Line expresses activated human ROS1 tyrosine kinase ETV6-ROS1 in MSCV-His-GFP vector . Ba/F3 cells expressing activated tyrosine kinase become completely dependent on the kinase activity for survival and as a result, the cells can be propagated even in the absence of IL-3.
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