GENERAL CATALOGUE
Rosuvastatin Calcium
HY-17504 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-17504
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Catalog No: HY-17504
CAS No: 147098-20-2
Category: Anti-infection
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Rosuvastatin Calcium is a competitive HMG-CoA reductase HMGCR inhibitor, with an IC50 of 11 nM. Rosuvastatin Calcium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Calcium reduces the expression of the mature hERG and the interaction of heat shock protein 70 Hsp70 with the hERG protein. Rosuvastatin Calcium effectively lowers low-density lipoprotein LDL cholesterol, triglycerides, and C-reactive protein levels.
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