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Roxindole hydrochloride
GENERAL CATALOGUE

Roxindole hydrochloride

HY-106100A · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-106100A

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Catalog No: HY-106100A
CAS No: 108050-82-4
Category: GPCR G Protein
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress

Description

Roxindole hydrochloride EMD 38362 , an indot-alkyl-pipenidine, is a potent agonist at dopamine autoreceptors, with an affinity for the D2-like subtype in the low nanomolar range. Roxindole can be used for the research of positive and negative schizophrenic symptoms. Roxindole is a 5-HT1A agonist and 5-HT uptake inhibitor with high affinity for 5-HT1A IC50=0.9 nM . Antipsychotic and antidepressant activities.

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