GENERAL CATALOGUE
RP-220
HY-P6084 · 50 mg
MedChemExpress · Cat: HY-P6084
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medchemexpress.com/rp-220.html
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Catalog No: HY-P6084
CAS No: 1541177-35-8
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
RP-220 is a renalase peptide targeting NLRP3. RP220 has anti-inflammatory and anti-apoptotic activities. RP220 inhibits renal tubular epithelial cells apoptosis with alkaline insult by activating MAPK signaling pathway. RP220 significantly inhibits NLRP3 expression and reduces macrophage infiltration and kidney tissue damage in acute kidney injury AKI mice model. RP-220 can be uses for systemic lupus erythematosus SLE and its complication lupus nephritis LN research.
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