RRM2B Rabbit Monoclonal Antibody

Description

EnkiLife offers the RRM2B Rabbit Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,IHC,IP application. Alternative Names of Immunogen: P53R2; MTDPS8A; MTDPS8B. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1000-1:5000,IHC 1:200-1:500,IP 1:10-1:100 Background: This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]