GENERAL CATALOGUE
RTI-7470-44
HY-147319 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-147319
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medchemexpress.com/rti-7470-44.html
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Catalog No: HY-147319
CAS No: 825658-63-7
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
RTI-7470-44 is a potent, selective and blood-brain barrier BBB penetrant human trace amine-associated receptor subtype 1 hTAAR1 antagonist with an IC50 value of 8.4 nM and a Ki value of 0.3 nM. RTI-7470-44 has moderate metabolic stability, and a favorable preliminary off-target profile. RTI-7470-44 can increase the spontaneous firing rate of mouse ventral tegmental area VTA dopaminergic neurons. RTI-7470-44 can be used for researching schizophrenia, agent addiction, and ParkinsonAAasAasAas disease PD .
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