

HY-145196 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-145196
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medchemexpress.com/rticbm-189.htmlDescription
RTICBM-189 is a potent, brain-penetrant allosteric modulator of the cannabinoid type-1 CB1 receptor with a pIC50 of 7.54 in Ca2+ mobilization assay. RTICBM-189 has pIC50s of 5.29 and 6.25 for hCB1 and mCB1, respectively. RTICBM-189 significantly and selectively attenuates the reinstatement of the addictive agent-seeking behavior in rats.







