GENERAL CATALOGUE
RTx-152
HY-161431 · 5 mg
MedChemExpress · Cat: HY-161431
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Catalog No: HY-161431
CAS No: 3035072-48-8
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
RTx-152 traps Pol? on DNA and is an allosteric Pol?-pol inhibitor IC50: 6.2 nM . RTx-152 selectively kills HR-deficient cancer cells, and suppresses PARP inhibitor resistance in multiple genetic backgrounds, including homologous recombination HR -proficient cells. RTx-152 selectively kills BRCA2-null cells.
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