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RU-521
ab287088 · 1 mg
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Catalog No: ab287088
Category: Biochemicals
Pack Size: 1 mg
Brand: abcam
Description
MW 415.2 Da, Purity >98 %. RU-521 RU-320521 is a potent, selective cyclic GMP-AMP synthase cGAS inhibitor Kd = 36.2 nM . RU-521 is active and selective in cellular assays of cyclic GMP-AMP synthase-mediated signaling and reduces constitutive expression of interferon in macrophages from a mouse model of Aicardi-Goutieres syndrome.
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