GENERAL CATALOGUE
RU.521
HY-114180 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-114180
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medchemexpress.com/ru-521.htmlCatalog No: HY-114180
CAS No: 2262452-06-0
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
RU.521 RU320521 is a potent and selective cyclic GMP-AMP synthase cGAS inhibitor and inhibits cGAS-mediated interferon upregulation. RU.521 suppresses dsDNA-activated reporter activity with an IC50 of 0.7 ?M. RU.521 reduces constitutive expression of interferon in macrophages from a mouse model of Aicardi-GoutiAAAasAA res syndrome AGS .
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