GENERAL CATALOGUE
Ru-Poma
HY-161668 · 50 mg
MedChemExpress · Cat: HY-161668
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Manufacturer product page
medchemexpress.com/ru-poma.htmlCatalog No: HY-161668
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Ru-Poma is a Ru II -based photosensitizer, which attenuates Cisplatin HY-17394 -resistant tumor through photodynamic therapy PDT . Ru-Poma photodegrades CRBN through a Pomalidomide HY-10984 moiety. Ru-Poma induces ferroptosis, through an increase in lipid peroxide, downregulation of GPX4 and GAPDH expression. Ru-Poma exhibits cytotoxicity in A549, with IC50 of 18.46 ?M and 0.37 ?M in dark and upon irradiation, respectively.
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