GENERAL CATALOGUE
Rubone
HY-119833 · 1 mg
MedChemExpress · Cat: HY-119833
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medchemexpress.com/rubone.html
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Catalog No: HY-119833
CAS No: 73694-15-2
Category: Epigenetics
Pack Size: 1 mg
Brand: MedChemExpress
Description
Rubone, a chalcone analog, is a modulator of miR-34a. Rubone upregulates miR-34a expression in a p53 dependent manner, downregulates the downstream target Bcl-2 and Cyclin D1 expression, and suppresses hepatocellular carcinoma HCC growth in vivo. Rubone enhances the anticancer effect of Paclitaxel PTX; HY-B0015 in PTX-resistant prostate cancer cell lines by reversing the expression of miR-34a downstream targets.
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