GENERAL CATALOGUE
Ruxolitinib
HY-50856 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-50856
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medchemexpress.com/Ruxolitinib.htmlCatalog No: HY-50856
CAS No: 941678-49-5
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Ruxolitinib INCB18424 is an orally active and selective JAK1/2 inhibitor with IC50s of 3.3 nM and 2.8 nM in cell-free assays, and has 130-fold selectivity for JAK1/2 over JAK3. Ruxolitinib induces autophagy and kills tumor cells through toxic mitophagy.
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