RYK Mouse Monoclonal Antibody

Description

EnkiLife offers the RYK Mouse Monoclonal Antibody. This antibody reacts with Human, Mouse species and is suitable for WB,FC application. Alternative Names of Immunogen: Tyrosine-protein kinase RYK, 2.7.10.1, RYK, JTK5A. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,FC 1:25-1:50 Background: May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C- terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development. Research Area: Wnt signaling pathway