
ab254235 · 1 mg
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Description
MW 284.3 Da, Purity >98 %. Inhibits IC50 = 500 nM KMT5A / SETD8 / Pr-SET7 and suppresses H4JK20 monomethylation in vitro. Weakly active against Cdk4 IC50 = 6 muM . Induces S-phase accumulation in HEK-293 cells. Cytotoxic towards a number of human cancer cell lines. May induce the DNA damage response.






