GENERAL CATALOGUE
S-095029
HY-P991610 · 1 mg
MedChemExpress · Cat: HY-P991610
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Manufacturer product page
medchemexpress.com/s-095029.htmlCatalog No: HY-P991610
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
S-095029 is a humanized IgG1 monoclonal antibody inhibitor targeting NKG2A. S-095029 significantly attenuates Fc-effector functions, inhibits the interaction with its ligand HLA-E, and increases the antibody-dependent cellular cytotoxicity mediated by other Fc-competent mAbs. S-095029 has a potent antitumor activity with enhancement of killing activity and cytokine secretion IFN?, TNF-? and CXCL9 of NK and ?? T-cells in co-culture with cancer cells.
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