

HY-172227 · 50 mg
MedChemExpress · Cat: HY-172227
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medchemexpress.com/s-15176.html
Description
S-15176 is an inhibitor of the mitochondrial permeability transition pore PTP . S-15176 inhibits mitochondrial swelling induced by tert-butylhydroperoxide with an IC50 value of 45.7 ?M. S-15176 inhibits PTP opening, prevents mitochondrial membrane potential dissipation and NAD P H oxidation, and increases mitochondrial calcium loading capacity. S-15176 is promising for research of ischemia-reperfusion injury.







