(S)-JQ-35

Description

S -JQ-35 TEN-010 is a selective bromodomain and extra-terminal domain BET protein family inhibitor targeting BRD4, BRD3, BRD2 and BRDT. S -JQ-35 is orally active and can penetrate the blood-brain barrier. S -JQ-35 competitively binds to the bromodomain of BRD4, preventing it from binding to the Myc gene promoter, thereby inhibiting cancer cell proliferation and inducing cell apoptosis. S -JQ-35 can be used for targeted therapy research of malignant tumors such as NUT midline carcinoma and refractory solid tumors.